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首頁 > 應(yīng)用案例 > UNIQSIS 連續(xù)流設(shè)備 > Publication 2: Continuous Flow Synthesis of Indoles by Pd-Mediated Reduction of o-Nitrostilbenes with Carbon Monoxide

Publication 2: Continuous Flow Synthesis of Indoles by Pd-Mediated Reduction of o-Nitrostilbenes with Carbon Monoxide

發(fā)布時間：2022-03-23 11:27:56瀏覽：48526次

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The Pd-mediated reduction of o-nitrostilbenes in the presence of carbon monoxide is reported to proceed regioselectively under pressurised flow-through conditions to cleanly afford indoles.

A variety of substrates are tolerated and the reaction proceeds significantly faster than in batch and produces carbon dioxide as the only stoichiometric side-product.

Publication 61Continuous Flow Synthesis of Indoles by Pd-Mediated Reduction of o-Nitrostilbenes with Carbon Monoxide.pdf

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